About Ketamine Infusion Therapy

Ketamine is an anesthetic drug that has been safely administered by anesthesiologists since 1970. Over the past 20 years, physicians have learned that ketamine can be used to treat a variety of conditions including:

  • Major depression
  • Post-traumatic stress disorder (PTSD)
  • Obsessive-compulsive disorder (OCD)
  • Chronic pain

At the AMG Ketamine & Wellness Center, we give hope to patients in the Nashville area who have not responded to other treatments for these conditions.

Plus, our center is different. We can give the higher and often more effective doses of ketamine only anesthesiologists can safely administer. That means a greater percentage of our patients will experience relief and often can go longer periods between maintenance infusions, saving money and lessening inconvenience.

Many patients for whom ketamine is effective in reducing pain are able to reduce the amount of pain medications they need to take, and some can entirely eliminate their dependence on opioid pain medicines.

How Ketamine Works

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Ketamine can work in three different ways to effectively treat pain and depression.

  1. It increases the amount of glutamate in the nervous system, which is an excitatory amino acid and neurotransmitter. This increases neuro connections so that the brain and spinal cord process pain in a healthier way, which also decreases depression.
  2. It resets pain receptors. With chronic pain, these receptors are turned on all the time. Ketamine quiets them down.
  3. It decreases the inflammation in the nervous system that contributes to pain and depression.

Our Team

The AMG Ketamine & Wellness Center is affiliated with Anesthesia Medical Group, the largest anesthesia provider group in Tennessee. AMG medical doctors provide ketamine infusions with safety and patient comfort as our top priority.

Every patient undergoes a comprehensive evaluation by an anesthesiologist, who closely oversees their individual care. Our team has significant experience developing highly effective ketamine infusion protocols while minimizing side effects.

Our staff provides support and comfort to patients. We fully explain each procedure so patients know what to expect. Treatment is constantly monitored by a nurse to ensure safety, and an anesthesiologist is always on site and immediately available.

Dr. Randall MalchowRandall Malchow, M.D.
Medical Doctor

Dr. Malchow served as an anesthesiologist for 25 years in the armed forces before retiring as a colonel in 2008. He then became an associate professor at Vanderbilt University Medical Center in Nashville, where he was the first Vanderbilt physician to offer intensive ketamine infusion therapy in 2014. In 2015, he established one of the few ketamine infusion centers (KIC) in the Veteran Health Administration and the only KIC in the U.S. specifically targeting opioid cessation/reduction.

He is an acknowledged U.S. expert on ketamine administration, having presented his extensive experience with ketamine in the veteran population at the American Society of Ketamine Physicians Annual Meeting in 2018. Dr. Malchow has published over 20 peer-reviewed journal articles and serves regularly on worldwide medical missions supporting those in need.

Dr. Malchow is honored to serve as the Medical Director for the AMG Ketamine & Wellness Center to provide compassionate and competent care for those suffering from depression, PTSD, OCD, chronic pain, and opioid dependence.

View Dr. Malchow’s Full CV

Our Location

1909 Mallory Lane, Suite 300
Franklin, TN 37067

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